Familial aggregation of FEF25-75 and FEF25-75/FVC in families with severe, early onset COPD
نویسندگان
چکیده
منابع مشابه
CHRONIC OBSTRUCTIVE PULMONARY DISEASE Familial aggregation of FEF25–75 and FEF25–75/FVC in families with severe, early onset COPD
Background: The Boston Early-Onset COPD study showed that current or ex-smoking first degree relatives of severe early onset COPD probands have significantly lower forced expiratory volume in 1 second (FEV1) and FEV1/forced vital capacity (FVC) values than current or ex-smoking control subjects, which suggests the existence of genetic risk factors for the development of COPD in response to ciga...
متن کاملPatterns of changes and diagnostic values of FEF50%, FEF25%-75% and FEF50%/FEF25%-75% ratio in patients with varying control of bronchial asthma.
BACKGROUND The pattern of change in FEF50%, FEF25%-75% and FEF50%/FEF25%-75% ratio depends on mechanics of forceful expiration, provided that non-homogenous lung emptying is faithfully recorded in the expiratory flow-volume loops. OBJECTIVE To assess the potential clinical value of FEF50%, FEF25%-75% and FEF50%/FEF25%-75% ratio as an indicator of bronchial asthma (BA) control. METHODOLOGY T...
متن کاملInflammation Markers and FEF25-75: A Relevant Link in Children With Asthma.
84 http://e-aair.org Jang and colleagues investigated the relationship between exhaled nitric oxide (FeNO) and atopy profiles in children with asthma. They focused their attention mainly on the FeNO, showing that this parameter varied according to the profile of atopy. The authors also investigated lung function, including bronchial hyperreactivity. However, forced vital capacity, forced expira...
متن کاملHigher BMI is associated with higher expiratory airflow normalised for lung volume (FEF25–75/FVC) in COPD
INTRODUCTION The obesity paradox in chronic obstructive pulmonary disease (COPD), whereby patients with higher body mass index (BMI) fare better, is poorly understood. Higher BMIs are associated with lower lung volumes and greater lung elastic recoil, a key determinant of expiratory airflow. The forced expiratory flow (25-75) (FEF25-75)/forced vital capacity (FVC) ratio reflects effort-independ...
متن کاملAssociation of parental FEF25-75% during a methacholine challenge and children's PC20 and diagnosis of asthma
Background There is evidence that paternal and maternal lung function influence children’s pulmonary function. To date, the most widely used pulmonary function test (PFT) to assess airway responsiveness is the PC20 (concentration of methacholine required to decrease FEV1 by 20%). However, other measures of parental lung function may be better predictors of airway responsiveness or asthma develo...
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ژورنال
عنوان ژورنال: Thorax
سال: 2004
ISSN: 0040-6376
DOI: 10.1136/thx.2003.012856